Factor XIa inhibition with asundexian after acute non-cardioembolic ischaemic stroke (PACIFIC-Stroke): an international, randomised, double-blind, placebo-controlled, phase 2b trial - The Lancet
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ESC 2022 – factor XI inhibitors crash
A Multicenter, Phase 2, Randomized, Placebo-Controlled, Double
Pharmacology and Clinical Development of Factor XI Inhibitors
Design and Preclinical Characterization Program toward Asundexian
(BAY 2433334) is an orally active coagulation factor Xia (FXIa) inhibitor. Asundexian binds directly, potently, and reversibly to the active site
Asundexian
Thromboinflammatory challenges in stroke pathophysiology
ESC 22: Dosing of Asundexian in Pts With Non-Cardioembolic
The Next Wave of Anticoagulation: Results of PACIFIC-AF and the
News at XI: moving beyond factor Xa inhibitors - ScienceDirect