Chemical and genetic rescue of an ep300 knockdown model for
Por um escritor misterioso
Descrição
Spermidine induces autophagy by inhibiting the acetyltransferase EP300
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma
Shruti Kapoor - Scientist - Cancer Biology
LINC01605, regulated by the EP300-SMYD2 complex, potentiates the binding between METTL3 and SPTBN2 in colorectal cancer, Cancer Cell International
Reducing histone acetylation rescues cognitive deficits in a mouse model of Fragile X syndrome
The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability - ScienceDirect
Chemical and genetic rescue of an ep300 knockdown model for Rubinstein Taybi Syndrome in zebrafish - ScienceDirect
, an analog of EX-527, is a potent and selective inhibitor of SIRT1 (IC50=0.124 µM). CHIC35 shows potential selective inhibition against SIRT1
CHIC35
Directional divergence of Ep300 duplicates in teleosts and its implications, BMC Ecology and Evolution
Frontiers Epigenetic disorders: Lessons from the animals–animal models in chromatinopathies
