How does SARS-CoV-2 evade the immune defences?
Por um escritor misterioso
Descrição
As most of pathogens, SARS-CoV-2 can be recognized by pattern recognition receptors on innate. Normally, this recognition helps the innate immunity to eliminate the infection or to activate the adaptive immune responses, however, SARS-CoV-2 can use its proteins such as M, N, NSP1 and PLpro to interfere with these pathways.
A review: Antibody-dependent enhancement in COVID-19: The not so friendly side of antibodies - Gabriela Athziri Sánchez-Zuno, Mónica Guadalupe Matuz-Flores, Guillermo González-Estevez, Ferdinando Nicoletti, Francisco Javier Turrubiates-Hernández, Katia
New Studies Find Evidence Of 'Superhuman' Immunity To COVID-19 In Some People : Goats and Soda : NPR
SARS-CoV-2 variants of concern partially escape humoral but not T cell responses in COVID-19 convalescent donors and vaccine recipients
The effects of SARS-CoV-2 infection on modulating innate immunity and strategies of combating inflammatory response for COVID-19 therapy, Journal of Biomedical Science
Does COVID really damage your immune system and make you more vulnerable to infections? The evidence is lacking
Innate immunity, cytokine storm, and inflammatory cell death in COVID-19, Journal of Translational Medicine
SARS-CoV-2 spike mutation L452R evades human
COVID-19, Predicted Immune responses
Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant
Frontiers Highlight of Immune Pathogenic Response and Hematopathologic Effect in SARS-CoV, MERS-CoV, and SARS-Cov-2 Infection