Cells, Free Full-Text
Por um escritor misterioso
Descrição
Silk has a long history as an exclusive textile, but also as a suture thread in medicine; nowadays, diverse cell carriers are manufactured from silk. Its advantages are manifold, including high biocompatibility, biomechanical strength and processability (approved for nearly all manufacturing techniques). Silk’s limitations, such as scarcity and batch to batch variations, are overcome by gene technology, which allows for the upscaled production of recombinant “designed” silk proteins. For processing thin fibroin filaments, the sericin component is generally removed (degumming). In contrast to many synthetic biomaterials, fibroin allows for superior cell adherence and growth. In addition, silk grafts demonstrate superior mechanical performance and long-term stability, making them attractive for anterior cruciate ligament (ACL) tissue engineering. Looking at these promising properties, this review focusses on the responses of cell types to silk variants, as well as their biomechanical properties, which are relevant for ACL tissue engineering. Meanwhile, sericin has also attracted increasing interest and has been proposed as a bioactive biomaterial with antimicrobial properties. But so far, fibroin was exclusively used for experimental ACL tissue engineering approaches, and fibroin from spider silk also seems not to have been applied. To improve the bone integration of ACL grafts, silk scaffolds with osteogenic functionalization, silk-based tunnel fillers and interference screws have been developed. Nevertheless, signaling pathways stimulated by silk components remain barely elucidated, but need to be considered during the development of optimized silk cell carriers for ACL tissue engineering.
Nt Novo Cella Get File - Colaboratory
Sequencing of Circulating Cell-free DNA during Pregnancy
The emerging impact of cell-free chemical biosynthesis - ScienceDirect
Ds Kumar Strömungsmechanik Pdf Kostenloser Download - Colaboratory
Cells, Free Full-Text
Biology, Free Full-Text
Remote immune processes revealed by immune-derived circulating cell-free DNA
Sequencing of Circulating Cell-free DNA during Pregnancy
The cell-free system: A new apparatus for affordable, sensitive, and portable healthcare - ScienceDirect
PDF) Comparative separation methods and biological characteristics of human placental and umbilical cord mesenchymal stem cells in serum-free culture conditions
Cell-free Fetal DNA — A Trigger for Parturition
Cell Circuits and Complex Tissues
